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Chosen to boost your immunity

Co-Defender is a unique formulation of potent and pure ingredients, including vitamins and minerals, important for the defensive immune system. It is packed with highly effective and immunomodulatory supplements that enhance the immune response against foreign agents and support optimal physiological functions. 

Co-Defender-Immunity Booster

Co-defender is specifically designed to boost the body immunity level and naturally increase body resistance, both innate and adaptive immunity against COVID-19. Additionally, it significantly upgrades and boosts the weak, fragile, and poor immune system.
The combination of highly researched supplements such as Vit D3, Zinc, Vit C, Vit A, Vit B family, and Selenium stimulates the production of the immune cells, preserves cellular integrity, and strengthens the immune system against various toxins and pathological agents, including viruses. We don't claim that our product prevents, treat or cure COVID-19, but lab studies and other research studies reported a significant role of the above supplements in the coronavirus infections, discussed later in the role of ingredients section.
The formulation is carefully prepared in a well-certified facility following strict GMP guidelines. Additionally, the end product is dually tested for purity, safety, and efficacy in a third-party lab. It is important to mention that there are no synthetic chemicals, gluten, or harmful additives in Co-Defender formulation. It is important to know that we added the optimum amount of piperine in our Co-Defender formulation to increase the gut absorption of certain nutrients.
Features of Co-Defender

  • Pure Nutrients Formulation
  • No risk of Side Effects
  • Free from Preservatives
  • Deliver Immunostimulatory Property
  • Naturally, Boost Immunity Level
  • Reduce the Risk of Infections
  • Enhance Innate and Adaptive Immunity
  • Stimulate Immune Cell Production
  • Beneficial for Both Men and Women
  • Piperine for Maximum Absorption in the GIT
  • Quality Product of Highly Researched Supplements

Role of Ingredients based on Research Studies
Based on medical research studies by qualified scientists, we will give an overview of each ingredient as an Immunomodulatory agent against pathological agents, including COVID-19.
Vitamin D3
Vit D3 helps the immune system, supports the immune response, and prevents the development of various medical conditions, including infections. It significantly inhibits viral replication, inhibits inflammation, and increases the level of immune cells, including T-regulatory cells, lymphocytes, macrophages, and dendritic cells. As a result, Vit D increases the body's immunity level (both innate and adaptive) against pathological agents and other toxic substances. Besides, studies reported an association of inadequate Vit D3 levels with various viral infections, including Hepatitis C, HIV, respiratory tract infections, and influenza [1, 2]. Other medical research studies linked low serum Vit D3 level or deficiency of Vit D3 with an increased risk of COVID-19 and disease severity [3]. Moreover, the optimal concentration of Vit D3 is associated with a reduced mortality rate (risk of death) and fewer chances of COVID-19 development [4, 8]. Some studies also suggested that COVID-19 induced inflammation results in the reduction of Vit D3 level and increases the disease severity or mortality rate [5]. Further, an observational study found that Vit D3, Vit B12, and Magnesium supplementation, combined with other therapeutic agents, in COVID-19 reduce the risk of disease severity, need for oxygenation, and intensive care therapy [6. 7].
Vitamin C
Vit C, an essential vitamin, is reported in many medical research studies as a potent and effective immunomodulatory agent (provide antiviral, antimicrobial, and antioxidant activity). It significantly enhances innate and adaptive immunity and increases the body's resistance against pathological agents [9-12]. Medical research studies reported that optimal intake of Vit C modulates the immune response, preserves cellular integrity, boosts B- and T- cells differentiation, suppresses inflammatory cytokines, and inhibits viral growth. Moreover, researchers suggest the use of Vit C as an adjuvant therapy (combined with standard treatment) in the management of COVID0-19 [9, 11]. Because it reduces inflammation, prevents vascular injury, decreases the common cold duration and severity, prevents the development of cold, helps support pneumonia treatment, and eliminates toxins in the body [13-16]. Additionally, medical research studies reported that Vit C supplementation, combined with other therapeutic options, reduces the mortality rate in COVID-19 patients, increases the antioxidant capacity, and suppresses the inflammatory cytokine (interleukin-6) or inflammation during COVID-19 [13-16].
Zinc (Zn)
Zinc is the highly investigated nutrient in the treatment of COVID-19. Along with other health benefits, Zn effectively modulates the body's immune response against various pathological agents and environmental hazards. It boosts innate and adaptive immune systems by providing antimicrobial, anti-inflammatory, antioxidant, and antiviral properties [17]. Studies showed that Zn deficiency impairs immune cells' activation, maturation, and production, including lymphocytes, T cells, natural killer cells, and macrophages [17-19]. Moreover, Zn deficient individuals are prone to inflammatory conditions, viral infections such as HIV, Hepatitis C, and respiratory diseases (pneumonia). Researchers believe that Zn supplementation might prevent the development of COVID-19 and disease or symptoms severity, such as lessening diarrhea and loss of smell and taste. Also, medical studies linked lower Zn levels with a high risk of death, delayed recovery, medical complications, and disease severity [23-25]. Further, proper supplementation of Zn showed positive outcomes in a study (involving COVID-19 patients) as it improved COVID-19 symptoms, including headache, cough, fever, fatigue, body aches, and shortness of breath [20-25].
Selenium (Se)
Selenium plays an important role in various physiological functions in the body. It significantly boosts both innate and adaptive immune systems via modulating or stimulating the immune cells in the body. Studies showed that Se helps T-cell maturation and activity of natural killer cells, preventing infections and other medical conditions [26-31]. Moreover, researchers suggest the use of selenium as adjuvant therapy for the management of COVID-19. Because various medical studies reported that Se, combined with standard treatment, reduces the overall mortality rate, need for hospitalization and provides significant positive outcomes as an antioxidant, anti-inflammatory, and antiviral agent [26, 27, 30-31]. Further, certain studies showed that low Se level in COVID-19 patients is linked with the worst symptoms; on the other hand, a higher level of Se COVID-19 patients is connected with a higher survival rate [30-33].
Vitamin E
Vit E, also known as alpha-tocopherol, acts as an effective antioxidant agent and enhances immunity. It helps the production of antibodies and also preserves optimal cellular integrity for better physiological functions. Medical research studies reported that Vit E boosts lymphocyte proliferation, potentiates natural killer cell activity, suppresses pro-inflammatory cytokines, and supports humoral and cell-mediated immunity [27, 34-35]. Moreover, studies also linked Vit E deficiency with a high risk of respiratory tract infections, while proper Vit E supplementation reduces the risk of pneumonia and upper respiratory tract infections, including common cold [36]. Additionally, research studies showed that Vit E, combined with other therapeutic agents or other nutrients, reduces inflammatory markers, the need for hospitalization, and the risk of cytokine storm in COVID-19 patients [36, 37].
N-Acetylcysteine (NAC)
NAC is an amino acid derivative evaluated in various studies for its antioxidant, antiviral and anti-inflammatory activity. It significantly boosts natural antioxidants level in the body, including glutathione, and also help suppress respiratory mucus level. Lab studies suggested that NAC effectively inhibits viral replication, enhances immune response, and suppresses inflammatory response [38-40]. Medical research studies reported that NAC intake helps improve bronchitis and chronic obstructive pulmonary disease (COPD) symptoms. Moreover, combined with standard COVID-19 treatment, NAC showed positive outcomes during COVID-19 by reducing the mortality rate and risk of progression to severe conditions [37, 41-43]. In contrast, certain studies didn't find any positive aspects of NAC; however, research suggests that NAC, combined with standard treatment, improves outcomes and helps COVID-19 treatment [38-41].
Vitamin A
Vit A, an essential vitamin, is also studied for COVID-19 along with other nutrients such as selenium, zinc, Vit D, and Vit E. Research studies reported that low serum Vit A is associated with a higher risk of COVID-19 mortalities, symptoms severity, and delayed recovery [44]. However, optimal supplementation of Vit A, combined with standard treatment and nutrient like Vit D, etc. help reduce the risk of death, need for hospitalization, shorten the duration of symptoms, inhibit SARs-CoV-2 replication (in lab studies), suppress inflammation, preserve respiratory epithelial integrity and help prevent disease progression [44-48].
Calcium not only improves the absorption of Vit D3 and other nutrients but also help enhance immunity level. Studies reported that a low level of Calcium is highly associated with COVID-19 disease severity and prognosis. Moreover, the optimal calcium concentration supports proper respiratory functioning, energy production, immune response, muscle contraction, and other vital physiological functions. Studies also hypothesized that Calcium supplementation might decrease the severity of COVID-19 symptoms and prevent the progression of the disease [50].
Vit B family
Vit B family, including Vit B1, B2, B3, B5, B6, B9, and B12, supports vital physiological functions and plays an important role in the activation of both innate and adaptive immunity. They significantly suppress the inflammatory response, preserve endothelial integrity, support respiratory function, prevent gastrointestinal and respiratory conditions, and also help decrease hospitalization. Thus, various research studies suggested that proper intake of Vit B family could help COVID-19 disease via reducing the risk of death, symptoms severity, need for oxygen, organs damage, and intensive care support [51].
Glutathione (GSH)
Glutathione supplementation restores natural antioxidant levels and regulates impaired redox homeostasis in the body disturbed by various medical conditions, including COVID-19. Studies demonstrated that GSH might suppress the COVID-19 induced inflammation, improve disease severity and prevent organ failure [52].
Yeah, clinical trials are underway to explore the exact immunomodulatory mechanisms and draw a final conclusion about the nutrients in our Co-Defender formulation. However, we can't deny the immunostimulatory actions of these nutrients reported in various in-vitro, in-vivo, observational, and clinical studies. Thus, we can proudly claim that our Co-Defender product is a unique immunostimulatory formulation in the market against various pathological agents.


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