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Selenium plays an important role in various physiological functions in the body. It significantly boosts both innate and adaptive immune systems via modulating or stimulating the immune cells in the body. Studies showed that Se helps T-cell maturation and activity of natural killer cells, preventing infections and other medical conditions [26-31]. Moreover, researchers suggest the use of selenium as adjuvant therapy for the management of COVID-19. Because various medical studies reported that Se, combined with standard treatment, reduces the overall mortality rate, need for hospitalization and provides significant positive outcomes as an antioxidant, anti-inflammatory, and antiviral agent [26, 27, 30-31]. Further, certain studies showed that low Se level in COVID-19 patients is linked with the worst symptoms; on the other hand, a higher level of Se COVID-19 patients is connected with a higher survival rate [30-33].

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  2. Alexander J, Tinkov A, Strand TA, Alehagen U, Skalny A, Aaseth J. Early nutritional interventions with zinc, selenium and vitamin D for raising anti-viral resistance against progressive COVID-19. Nutrients 2020;12.
  3. Notz Q, Herrmann J, Schlesinger T, Helmer P, Sudowe S, Sun Q, et al. Clinical Significance of Micronutrient Supplementation in Critically Ill COVID-19 Patients with Severe ARDS. Nutrients 2021;13.
  4. Moghaddam A, Heller RA, Sun Q, Seelig J, Cherkezov A, Seibert L, et al. Selenium Deficiency Is Associated with Mortality Risk from COVID-19. Nutrients 2020;12.

Vitamin E
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